>> P-797: Epidemiological profile DNA HPV16 positive women
19:00 PM - 19:00 PM
Maria I. Rosa1, Mary C. Bozzetti4, Fabio R. Silva3, Lidia R. Medeiros2, Bruno R. Silva3, Priscila Seibert3, Priscyla W. Simões1.
1Laboratory of Epidemiology and National Institute for Translational Medicine, Postgraduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, Criciúma, SC, Brazil; 2Hospital Fêmina and Hospital Moinhos de Vento, Porto Alegre, Brazil; 3Laboratory of Epidemiology, University of Southern Santa Catarina, Criciúma, SC, Brazil; 4Postgraduate Program in Epidemiology at Federal University of Rio Grande do Sul, Porto Alegre, Brazil.
Introduction: Human papillomavirus (HPV) infection has been established as the most important cause of cervical cancer. The annual incidence of cervical cancer varies among different regions of the world, estimated to be around 11,000 in the United States of America (USA) and 19,000 in Brazil.
Objective: To determine the epidemiological profile of HPV-16 positive women.
Methods: Cross-sectional study of 1433 asymptomatic women attending a primary care clinic in the city of Porto Alegre, Southern Brazil. Cervical smears were collected to perform HPV DNA detection.
Results: The prevalence of all HPVs was 25.3% (11.3% HPV-16). The average age of women who had HPV-16 was 41.4 (± 13.1), 80.6% were white, 50% had stable marital status. 93.5% used oral contraceptives, 72.6% had the first sexual intercourse under 20 years. 79.0 had at least one pregnancy, 66.1% reported having had only one partner in the last month and 33.9% reported having had more than 4 partners in life. 12.9% partners had warts. The PCR for Chlamydia trachomatis was positive and 58.1% had candidiasis vulvovaginal. 37.1% were smokers. Age less than 41 years (p = 0.032) and partner with warts (p = 0.033) were the only variables that had differences between HPV positive women with other types of HPV and HPV16.
Conclusion: The epidemiological profile of HPV DNA positive women are similar except for age and presence of warts on partner that are shown to be different in the HPV16 .
